ADAM9 antibody (C-Term)

Catalog No. ABIN2841552

There is 1 publication for this product available. The Rabbit Polyclonal anti-ADAM9 antibody is suitable to detect ADAM9 in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for ADAM9 antibody (C-Term) (ABIN2841552)

Target: ADAM9 (ADAM Metallopeptidase Domain 9 (ADAM9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM9 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB17777

Product Details anti-ADAM9 Antibody

Binding Specificity: AA 704-733, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ADAM9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 704-733 amino acids from the C-terminal region of human ADAM9.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-ADAM9 antibody (ABIN2841552)

Xiang, Ou, Liu, Chen, Li, Huang, Yang: "Loss of tumor suppressor miR-126 contributes to the development of hepatitis B virus-related hepatocellular carcinoma metastasis through the upregulation of ADAM9." in: Tumour biology, Vol. 39, Issue 6, pp. 1010428317709128, (2017) (PubMed).

Target Details for ADAM9

Target: ADAM9 (ADAM Metallopeptidase Domain 9 (ADAM9))

Alternative Name: ADAM9

Background: ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

Molecular Weight: 90556

Gene ID: 8754

NCBI Accession: NP_003807

UniProt: Q13443

Pathways: Cellular Response to Molecule of Bacterial Origin, SARS-CoV-2 Protein Interactome