ATP5C1 antibody (N-Term)

Catalog No. ABIN653186

There is 1 publication for this product available. The Rabbit Polyclonal anti-ATP5C1 antibody is suitable to detect ATP5C1 in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for ATP5C1 antibody (N-Term) (ABIN653186)

Target: ATP5C1 (ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, gamma Polypeptide 1 (ATP5C1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP5C1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB23852

Product Details anti-ATP5C1 Antibody

Binding Specificity: AA 40-67, N-Term

Predicted Reactivity: B, Pr, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP5C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-67 amino acids from the N-terminal region of human ATP5C1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-ATP5C1 antibody (ABIN653186)

Magalon, Le Grand, El Waly, Moulis, Pruss, Bordet, Cayre, Belenguer, Carré, Durbec: "Olesoxime favors oligodendrocyte differentiation through a functional interplay between mitochondria and microtubules." in: Neuropharmacology, Vol. 111, pp. 293-303, (2017) (PubMed).

Target Details for ATP5C1

Target: ATP5C1 (ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, gamma Polypeptide 1 (ATP5C1))

Alternative Name: ATP5C1

Background: ATP5C1 encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3.

Molecular Weight: 32996

Gene ID: 509

NCBI Accession: NP_001001973, NP_005165

UniProt: P36542

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process