ID4 antibody (N-Term)

Catalog No. ABIN653935

Product Details anti-ID4 Antibody

Target: ID4 (Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ID4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Pig

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ID4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ID4.

Clone: RB24654

Isotype: IgG

Application Details

Application Notes: FC: 1:10~50. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ID4

Target: ID4 (Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4))

Alternative Name: ID4 (ID4 Products)

Synonyms: Idb4 antibody, bHLHb27 antibody, cb547 antibody, fb77d04 antibody, sb:cb547 antibody, wu:fb77d04 antibody, zgc:123214 antibody, bhlhb27 antibody, id4 antibody, id4a antibody, idb4 antibody, IDB4 antibody, inhibitor of DNA binding 4 antibody, inhibitor of DNA binding 4, HLH protein antibody, inhibitor of DNA binding 4, HLH protein S homeolog antibody, Id4 antibody, id4 antibody, id4.S antibody, ID4 antibody

Background: ID4 is transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins

Molecular Weight: 16622

Gene ID: 3400

NCBI Accession: NP_001537

UniProt: P47928