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Mediator Complex Subunit 25 (MED25) (AA 112-140) antibody Primary Antibody

MED25 Reactivity: Human, Mouse IHC (p), WB Host: Rabbit Polyclonal RB24225 unconjugated
Pubmed (1)
Catalog No. ABIN654162
$423.50
Plus shipping costs $45.00
400 μL ABIN654162
400 μL ABIN654162
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  • Target
    Mediator Complex Subunit 25 (MED25)
    Binding Specificity
    • 12
    • 11
    • 8
    • 3
    • 1
    AA 112-140
    Reactivity
    • 26
    • 16
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 26
    Rabbit
    Clonality
    • 26
    Polyclonal
    Conjugate
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Un-conjugated
    Application
    • 21
    • 17
    • 14
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Predicted Reactivity
    B
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MED25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-140 amino acids of human MED25.
    Clone
    RB24225
    Isotype
    IgG
  • Application Notes
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Han, Rha, Chi: "MED25 is a mediator component of HNF4α-driven transcription leading to insulin secretion in pancreatic beta-cells." in: PLoS ONE, Vol. 7, Issue 8, pp. e44007, 2013 (PubMed). Method employed by authors: Western Blotting (WB)

  • Target
    Mediator Complex Subunit 25 (MED25)
    Alternative Name
    MED25 (MED25 Antibody Abstract)
    Synonyms
    Arc92, CG12254, Dmel\\CG12254, LD07688, Med25, dARC92, dDrip97, med25, ACID1, ARC92, CMT2B2, P78, PTOV2, RGD1305137, 2610034E13Rik, 2610529E18Rik, ESTM2, X83308, zgc:63555, Mediator complex subunit 25, mediator complex subunit 25, mediator complex subunit 25 S homeolog, MED25, med25, Med25, med25.S
    Background
    This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq].
    Molecular Weight
    78171
    Gene ID
    81857
    NCBI Accession
    NP_112235
    UniProt
    Q71SY5
    Pathways
    Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response
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