Claudin 22 (CLDN22) (AA 90-117) antibody

Catalog No. ABIN654190

This Rabbit Polyclonal antibody specifically detects in WB and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for Claudin 22 (CLDN22) (AA 90-117) antibody (ABIN654190)

Target: Claudin 22 (CLDN22)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB25720

Product Details

Binding Specificity: AA 90-117

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CLDN22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-117 amino acids of human CLDN22.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: Claudin 22 (CLDN22)

Alternative Name: CLDN22

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand.

Molecular Weight: 24509

Gene ID: 53842

NCBI Accession: NP_001104789

UniProt: Q8N7P3

Pathways: Cell-Cell Junction Organization, Hepatitis C