Iba1 antibody (N-Term)

Catalog No. ABIN654407

There are 2+ publications for this product available. The Rabbit Polyclonal anti-Iba1 antibody is suitable to detect Iba1 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for Iba1 antibody (N-Term) (ABIN654407)

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Iba1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB14652

Product Details anti-Iba1 Antibody

Binding Specificity: AA 6-36, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-36 amino acids from the N-terminal region of human AIF1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-Iba1 antibody (ABIN654407)

Ye, Miao, Lu, Xia, Chen, Zhang, Wu, He, Qiang, Zhou: "Allograft inflammatory factor-1 is an independent prognostic indicator that regulates β-catenin in gastric cancer." in: Oncology reports, Vol. 31, Issue 2, pp. 828-34, (2013) (PubMed).

DiFranco, Gupta, Galusha, Perez, Nguyen, Fineza, Kachlany: "Leukotoxin (Leukothera®) targets active leukocyte function antigen-1 (LFA-1) protein and triggers a lysosomal mediated cell death pathway." in: The Journal of biological chemistry, Vol. 287, Issue 21, pp. 17618-27, (2012) (PubMed).

Target Details for Iba1

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Alternative Name: AIF1

Background: AIF1 is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma.

Molecular Weight: 16703

Gene ID: 199

NCBI Accession: NP_001614, NP_004838, NP_116573

UniProt: P55008

Pathways: Smooth Muscle Cell Migration