CASC4 antibody (C-Term)

Catalog No. ABIN654468

Product Details anti-CASC4 Antibody

Target: CASC4 (Cancer Susceptibility Candidate 4 (CASC4))

Binding Specificity: AA 336-365, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASC4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CASC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human CASC4.

Clone: RB28633

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CASC4

Target: CASC4 (Cancer Susceptibility Candidate 4 (CASC4))

Alternative Name: CASC4 (CASC4 Products)

Synonyms: H63 antibody, D130060C09Rik antibody, VGFG2573 antibody, cancer susceptibility 4 antibody, cancer susceptibility candidate 4 antibody, cancer susceptibility 4 L homeolog antibody, CASC4 antibody, Casc4 antibody, casc4.L antibody

Background: The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30 % of human breast and 20 % of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene.

Molecular Weight: 49498

Gene ID: 113201

NCBI Accession: NP_612432, NP_816929

UniProt: Q6P4E1