IBTK antibody (AA 586-613)

Catalog No. ABIN654688

This Rabbit Polyclonal antibody specifically detects IBTK in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for IBTK antibody (AA 586-613) (ABIN654688)

Target: IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IBTK antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB24652

Product Details anti-IBTK Antibody

Binding Specificity: AA 586-613

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IBTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-613 amino acids from the Central region of human IBTK.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for IBTK

Target: IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Alternative Name: IBTK

Background: The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.

Molecular Weight: 150528

Gene ID: 25998

NCBI Accession: NP_056340

UniProt: Q9P2D0