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SPACA1 antibody (N-Term)

SPACA1 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB25586 unconjugated
Catalog No. ABIN654730
  • Target See all SPACA1 Antibodies
    SPACA1 (Sperm Acrosome Associated 1 (SPACA1))
    Binding Specificity
    • 13
    • 7
    • 5
    • 1
    • 1
    AA 46-74, N-Term
    Reactivity
    • 22
    • 1
    • 1
    Human
    Host
    • 22
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    This SPACA1 antibody is un-conjugated
    Application
    • 16
    • 15
    • 15
    • 12
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SACA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human SACA1.
    Clone
    RB25586
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    SPACA1 (Sperm Acrosome Associated 1 (SPACA1))
    Alternative Name
    SACA1 (SPACA1 Products)
    Synonyms
    SAMP32 antibody, 1700124L11Rik antibody, 4930540L03Rik antibody, sperm acrosome associated 1 antibody, SPACA1 antibody, Spaca1 antibody
    Background
    The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.
    Molecular Weight
    32143
    Gene ID
    81833
    NCBI Accession
    NP_112222
    UniProt
    Q9HBV2
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