DFNB31 antibody (AA 378-406)

Catalog No. ABIN655065

Product Details anti-DFNB31 Antibody

Target: DFNB31 (Deafness, Autosomal Recessive 31 (DFNB31))

Binding Specificity: AA 378-406

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DFNB31 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DFNB31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the Central region of human DFNB31.

Clone: RB19059

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for DFNB31

Target: DFNB31 (Deafness, Autosomal Recessive 31 (DFNB31))

Alternative Name: DFNB31 (DFNB31 Products)

Synonyms: DFNB31 antibody, CIP98 antibody, PDZD7B antibody, USH2D antibody, WHRN antibody, WI antibody, Cip98 antibody, Whrn antibody, 1110035G07Rik antibody, AW122018 antibody, AW742671 antibody, C430046P22Rik antibody, Dfnb31 antibody, wi antibody, whirlin antibody, WHRN antibody, LOC100555508 antibody, Whrn antibody

Background: This gene is thought to function in the organization and stabilization of sterocilia elongation and actin cystoskeletal assembly, based on studies of the related mouse gene. Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Molecular Weight: 96558

Gene ID: 25861

NCBI Accession: NP_001077354, NP_001166896, NP_056219

UniProt: Q9P202

Pathways: Sensory Perception of Sound