HNF1B antibody (C-Term)

Catalog No. ABIN655066

This Rabbit Polyclonal antibody specifically detects HNF1B in WB. It exhibits reactivity toward Human.

Quick Overview for HNF1B antibody (C-Term) (ABIN655066)

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF1B antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB19184

Product Details anti-HNF1B Antibody

Binding Specificity: AA 498-529, C-Term

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HNF1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-529 amino acids from the C-terminal region of human HNF1B.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for HNF1B

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Alternative Name: HNF1B

Background: This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 61324

Gene ID: 6928

NCBI Accession: NP_000449, NP_001159395

UniProt: P35680

Pathways: Hormone Transport, Stem Cell Maintenance, Tube Formation