Serotonin Receptor 2B antibody (C-Term)

Catalog No. ABIN655076

There is 1 publication for this product available. The Rabbit Polyclonal anti-Serotonin Receptor 2B antibody is suitable to detect Serotonin Receptor 2B in samples from Human, Mouse and Rat. It has been validated for WB and IHC (p).

Quick Overview for Serotonin Receptor 2B antibody (C-Term) (ABIN655076)

Target: Serotonin Receptor 2B (HTR2B)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB20470

Product Details anti-Serotonin Receptor 2B Antibody

Binding Specificity: AA 408-435, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HTR2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-435 amino acids from the C-terminal region of human HTR2B.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:2000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-Serotonin Receptor 2B antibody (ABIN655076)

Li, Sun, Li, Zhai, Wang, Chen, Lu: "Chronic restraint stress reduces carbon tetrachloride-induced liver fibrosis." in: Experimental and therapeutic medicine, Vol. 11, Issue 6, pp. 2147-2152, (2016) (PubMed).

Target Details for Serotonin Receptor 2B

Target: Serotonin Receptor 2B (HTR2B)

Alternative Name: HTR2B

Background: Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets, central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.

Molecular Weight: 54298

Gene ID: 3357

NCBI Accession: NP_000858

UniProt: P41595

Pathways: JAK-STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process