Endoglin antibody (AA 265-294)

Catalog No. ABIN655186

This Rabbit Polyclonal antibody specifically detects Endoglin in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for Endoglin antibody (AA 265-294) (ABIN655186)

Target: Endoglin (ENG)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB20948

Product Details anti-Endoglin Antibody

Binding Specificity: AA 265-294

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ENG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the Central region of human ENG.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: ENG

Background: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 70578

Gene ID: 2022

NCBI Accession: NP_000109, NP_001108225, NP_001265067

UniProt: P17813