IRF9 antibody (AA 75-104)
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- Target See all IRF9 Antibodies
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
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Binding Specificity
- AA 75-104
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IRF9 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This IRF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids of human IRF9.
- Clone
- RB19229
- Isotype
- Ig Fraction
- Top Product
- Discover our top product IRF9 Primary Antibody
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- Application Notes
- IF: 1:10~50. WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
- Alternative Name
- IRF9 (IRF9 Products)
- Background
- IRF9 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
- Molecular Weight
- 43696
- Gene ID
- 10379
- NCBI Accession
- NP_006075
- UniProt
- Q00978
- Pathways
- JAK-STAT Signaling, Interferon-gamma Pathway, Hepatitis C
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