Serotonin Receptor 3A antibody (N-Term)

Catalog No. ABIN656126

The Rabbit Polyclonal anti-Serotonin Receptor 3A antibody is suitable to detect Serotonin Receptor 3A in samples from Human. It has been validated for WB.

Quick Overview for Serotonin Receptor 3A antibody (N-Term) (ABIN656126)

Target: Serotonin Receptor 3A (HTR3A)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 3A antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB32257

Product Details anti-Serotonin Receptor 3A Antibody

Binding Specificity: AA 30-58, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HTR3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human HTR3A.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Serotonin Receptor 3A

Target: Serotonin Receptor 3A (HTR3A)

Alternative Name: HTR3A

Background: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 55280

Gene ID: 3359

NCBI Accession: NP_000860, NP_001155244, NP_998786

UniProt: P46098

Pathways: Synaptic Membrane