SNX13 antibody (C-Term)

Catalog No. ABIN656178

The Rabbit Polyclonal anti-SNX13 antibody (Clone RB32232) (ABIN656178) specifically detects SNX13 in WB. The antibody is reactive with Human samples.

Quick Overview for SNX13 antibody (C-Term) (ABIN656178)

Target: SNX13 (Sorting Nexin 13 (SNX13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX13 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB32232

Product Details anti-SNX13 Antibody

Binding Specificity: AA 780-807, C-Term

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SNX13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 780-807 amino acids from the C-terminal region of human SNX13.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: SNX13 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for SNX13

Target: SNX13 (Sorting Nexin 13 (SNX13))

Alternative Name: SNX13

Background: This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.

Molecular Weight: 112189

Gene ID: 23161

NCBI Accession: NP_055947

UniProt: Q9Y5W8

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling