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SNX13 antibody

SNX13 Reactivity: Human, Mouse IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7256382
  • Target See all SNX13 Antibodies
    SNX13 (Sorting Nexin 13 (SNX13))
    Reactivity
    Human, Mouse
    Host
    • 17
    • 3
    Rabbit
    Clonality
    • 19
    • 1
    Polyclonal
    Conjugate
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    This SNX13 antibody is un-conjugated
    Application
    • 20
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human SNX13 (NP_055947.1).
    Isotype
    IgG
    Top Product
    Discover our top product SNX13 Primary Antibody
  • Application Notes
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SNX13 (Sorting Nexin 13 (SNX13))
    Alternative Name
    SNX13 (SNX13 Products)
    Synonyms
    MGC142644 antibody, DKFZp469H181 antibody, Rgs-px1 antibody, mKIAA0713 antibody, RGS-PX1 antibody, sorting nexin 13 antibody, SNX13 antibody, Snx13 antibody
    Background
    This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.
    Gene ID
    23161
    UniProt
    Q9Y5W8
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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