KDM5A antibody (C-Term)

Catalog No. ABIN656192

The Rabbit Polyclonal anti-KDM5A antibody has been validated for WB and IHC (p). It is suitable to detect KDM5A in samples from Human.

Quick Overview for KDM5A antibody (C-Term) (ABIN656192)

Target: KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM5A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB10761

Product Details anti-KDM5A Antibody

Binding Specificity: AA 1609-1641, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This JARID1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1609-1641 amino acids from the C-terminal region of human JARID1A.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: JARID1A Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for KDM5A

Target: KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

Alternative Name: JARID1A

Background: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein.

Gene ID: 5927

UniProt: A8MUS2

Pathways: Chromatin Binding, Warburg Effect