KDM5A antibody (C-Term)

Catalog No. ABIN952968

Product Details anti-KDM5A Antibody

Target: KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

Binding Specificity: AA 1608-1641, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM5A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human JARID1A (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 1608-1641 amino acids from the C-terminal region of Human JARID1A Genename: KDM5A

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KDM5A

Target: KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

Alternative Name: JARID1A (KDM5A Products)

Synonyms: Jarid1a antibody, JARID1A antibody, RBBP-2 antibody, RBBP2 antibody, RBP2 antibody, AA409370 antibody, C76986 antibody, Rbbp2 antibody, lysine demethylase 5A antibody, lysine (K)-specific demethylase 5A antibody, Kdm5a antibody, KDM5A antibody

Background: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein.Synonyms: KDM5A

Molecular Weight: 186,838 Da

Gene ID: 5927

NCBI Accession: NP_005047

Pathways: Chromatin Binding, Warburg Effect