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BRAF antibody (B-Raf proto-oncogene, serine/threonine kinase) Primary Antibody

BRAF Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6566465
$438.90
Plus shipping costs $45.00
200 μL ABIN6566465
200 μL ABIN6566465
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days
  • Target
    BRAF
    Reactivity
    Human, Mouse, Rat
    • 215
    • 64
    • 49
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Host
    Rabbit
    • 189
    • 26
    • 2
    Clonality
    Polyclonal
    • 179
    • 38
    Conjugate
    This BRAF antibody is un-conjugated
    • 113
    • 19
    • 15
    • 13
    • 9
    • 9
    • 9
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Application
    Western Blotting (WB)
    • 136
    • 123
    • 88
    • 38
    • 33
    • 26
    • 21
    • 11
    • 10
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human BRAF
    Isotype
    IgG
  • Application Notes
    WB 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    BRAF
    Alternative Name
    BRAF (BRAF Antibody Abstract)
    Synonyms
    B-RAF1, BRAF1, NS7, RAFB1, C-RMIL, RMIL, B-Raf, braf1, rafb1, b-raf1, sierrabraf, BRAF, 9930012E13Rik, AA120551, AA387315, AA473386, B-raf, Braf-2, Braf2, C230098H17, C87398, D6Ertd631e, braf, fc48g01, wu:fc48g01, B-Raf proto-oncogene, serine/threonine kinase, B-Raf proto-oncogene, serine/threonine kinase S homeolog, Braf transforming gene, si:dkey-222f8.3, BRAF, Braf, braf.S, braf, si:dkey-222f8.3
    Background

    Synonyms: FLJ95109,94 kDa B raf protein,B raf 1,B Raf proto oncogene serine threonine protein kinase,B Raf proto oncogene,serine/threonine kinase,B RAF1,B-Raf proto-oncogene serine/threonine-protein kinase (p94),BRAF 1,BRAF,BRAF,BRAF1,cRmil,MGC126806,MGC138284,Murine sarcoma viral (v-raf) oncogene homolog B1,Murine sarcoma viral v raf oncogene homolog B1,NS7,Oncogen BRAF,oncogene BRAF1,p94,Proto-oncogene B-Raf,Proto-oncogene c-Rmil,RAFB 1,RAFB1,RMIL,Serine/threonine-protein kinase B-raf,v raf murine sarcoma viral oncogene homolog B,v raf murine sarcoma viral oncogene homolog B1,v-Raf murine sarcoma viral oncogene homolog B1

    Background: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

    Molecular Weight

    Observed_MW: 98kDa

    Calculated_MW: 84kDa

    Gene ID
    673
    UniProt
    P15056
    Pathways
    MAPK Signaling, RTK Signaling, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
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