BRAF Products
(B-Raf proto-oncogene, serine/threonine kinase (BRAF))
Categories
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008].
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Featured BRAF Categories
BRAF Antibodies
High quality antibodies with extensive validation data.
BRAF ELISA Kits
Reliable ELISA kits for a wide range of species.
BRAF Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BRAF Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Monkey
Application
WB, IHC, IHC (p), IF, FACS
Validations
- (9)
Cat. No.
ABIN1496951
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Rat
Application
WB, IHC, IHC (p), IF
Validations
- (8)
Cat. No.
ABIN1496954
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human
Application
WB, IHC, IHC (p)
Validations
- (18)
Cat. No.
ABIN1496961
Quantity
100 μL
Datasheet
Datasheet
Recommended BRAF ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962346
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954037
Quantity
96 tests
Datasheet
Datasheet
Recommended BRAF Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (2)
Cat. No.
ABIN5570026
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (2)
Cat. No.
ABIN5570024
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
Cat. No.
ABIN5570017
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our BRAF products
: "Protein expression of KIT, BRAF, GNA11, GNAQ and RASSF1 in feline diffuse iris melanomas." in: Veterinary journal (London, England : 1997), Vol. 249, pp. 33-40, (2019) (PubMed).: "Newly Identified BRAF Mutation in Rheumatoid Arthritis." in: Arthritis & rheumatology (Hoboken, N.J.), Vol. 68, Issue 6, pp. 1377-83, (2016) (PubMed).
: "Histologic and immunohistochemical predictors of clinical behavior for feline diffuse iris melanoma." in: Veterinary ophthalmology, Vol. 19 Suppl 1, pp. 44-55, (2016) (PubMed).
: "The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux." in: Autophagy, Vol. 11, Issue 8, pp. 1373-88, (2015) (PubMed).
: "HNF4? is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer." in: Gut, (2014) (PubMed).
: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).
: "TRIM59, a novel multiple cancer biomarker for immunohistochemical detection of tumorigenesis." in: BMJ open, Vol. 2, Issue 5, (2012) (PubMed).
: "BRAF drives synovial fibroblast transformation in rheumatoid arthritis." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34299-303, (2010) (PubMed).
: "Calcineurin increases glucose activation of ERK1/2 by reversing negative feedback." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 51, pp. 22314-9, (2010) (PubMed).
: "Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 26, Issue 35, pp. 5705-12, (2008) (PubMed).
Synonyms and alternative names related to BRAF
B-Raf proto-oncogene, serine/threonine kinase (BRAF), B-Raf proto-oncogene, serine/threonine kinase (Braf), B-Raf proto-oncogene, serine/threonine kinase S homeolog (braf.S), B-Raf proto-oncogene, serine/threonine kinase (braf), Braf transforming gene (Braf), si:dkey-222f8.3 (si:dkey-222f8.3), 9930012E13Rik, AA120551, AA387315, AA473386, B-Raf, B-raf, B-RAF1, b-raf1, BRAF, braf, Braf-2, BRAF1, braf1, Braf2, C-RMIL, C87398, C230098H17, D6Ertd631e, fc48g01, NS7, RAFB1, rafb1, RMIL, sierrabraf, wu:fc48g01Protein level used designations for BRAF
- 94 kDa B-raf protein
- B-Raf proto-oncogene serine/threonine-protein kinase (p94)
- murine sarcoma viral (v-raf) oncogene homolog B1
- proto-oncogene B-Raf
- serine/threonine-protein kinase B-raf
- v-raf murine sarcoma viral oncogene homolog B1
- B-Raf
- B-Raf proto-oncogene serine/threonine-protein kinase
- proto-oncogene c-Rmil
- rmil serine/threonine-protein kinase
- serine/threonine kinase
- serine/threonine-protein kinase Rmil
- serine/threonine protein kinase BRAF
- serine/threonine-protein kinase B-raf-like
- B-raf protein
- uncharacterized protein LOC561722
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