BRAF antibody (V-Raf Murine Sarcoma Viral Oncogene Homolog B1)

Details for Product anti-BRAF Antibody No. ABIN6566465
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
407
119
90
13
9
3
3
2
1
1
1
1
Host
Rabbit
320
84
4
Clonality
Polyclonal
Conjugate
This BRAF antibody is un-conjugated
23
20
19
16
16
16
6
6
6
6
6
6
2
2
2
2
2
Application
Western Blotting (WB)
276
223
172
69
68
43
26
22
13
6
4
3
2
1
1
1
Options
Immunogen Recombinant protein of human BRAF
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name BRAF (BRAF Antibody Abstract)
Background

Synonyms: FLJ95109,94 kDa B raf protein,B raf 1,B Raf proto oncogene serine threonine protein kinase,B Raf proto oncogene,serine/threonine kinase,B RAF1,B-Raf proto-oncogene serine/threonine-protein kinase (p94),BRAF 1,BRAF,BRAF,BRAF1,cRmil,MGC126806,MGC138284,Murine sarcoma viral (v-raf) oncogene homolog B1,Murine sarcoma viral v raf oncogene homolog B1,NS7,Oncogen BRAF,oncogene BRAF1,p94,Proto-oncogene B-Raf,Proto-oncogene c-Rmil,RAFB 1,RAFB1,RMIL,Serine/threonine-protein kinase B-raf,v raf murine sarcoma viral oncogene homolog B,v raf murine sarcoma viral oncogene homolog B1,v-Raf murine sarcoma viral oncogene homolog B1

Background: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Molecular Weight

Observed_MW: 98kDa

Calculated_MW: 84kDa

Gene ID 673
UniProt P15056
Pathways MAPK Signaling, RTK Signaling, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) antibody (ABIN6566465) Western blot analysis of extracts of various cell lines, using BRAF antibody.