Progesterone Receptor antibody

Catalog No. ABIN6566573

The Rabbit Polyclonal anti-Progesterone Receptor antibody has been validated for IHC. It is suitable to detect Progesterone Receptor in samples from Human, Rat and Mouse.

Quick Overview for Progesterone Receptor antibody (ABIN6566573)

Target: Progesterone Receptor (PGR)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Progesterone Receptor Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PGR (NP_000917.3).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: PGR

Background: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.

Molecular Weight:

Observed_MW: 100kDa

Calculated_MW: 36kDa/38kDa/82kDa/87kDa/98kDa

Gene ID: 5241

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration