LOXL1 antibody (Lysyl Oxidase-Like 1)

Details for Product anti-LOXL1 Antibody No. ABIN6566806
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
73
25
11
4
4
3
3
2
2
1
Host
Rabbit
76
7
Clonality
Polyclonal
Conjugate
This LOXL1 antibody is un-conjugated
11
9
3
2
2
2
2
2
2
Application
Western Blotting (WB)
65
30
21
10
7
6
5
4
3
2
2
1
Options
Immunogen Recombinant protein of human LOXL1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name LOXL1 (LOXL1 Antibody Abstract)
Background

Synonyms: Lysyl oxidase like 1,LOL,LOXL,Lysyl oxidase homolog 1,Lysyl oxidase like protein 1

Background: This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.

Molecular Weight

Observed_MW: 80kDa

Calculated_MW: 63kDa

Gene ID 4016
UniProt Q08397
Application Notes WB 1:1000 - 1:3000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Lysyl Oxidase-Like 1 (LOXL1) antibody (ABIN6566806) Western blot analysis of extracts of various cell lines, using LOXL1 antibody.