SYK antibody (AA 268-305)

Catalog No. ABIN656690

The Rabbit Polyclonal anti-SYK antibody is suitable to detect SYK in samples from Human and Mouse. It has been validated for WB.

Quick Overview for SYK antibody (AA 268-305) (ABIN656690)

Target: SYK (Spleen tyrosine Kinase (SYK))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYK antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB36961

Product Details anti-SYK Antibody

Binding Specificity: AA 268-305

Predicted Reactivity: Pig

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SYK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-305 amino acids from human SYK.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: SYK Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for SYK

Target: SYK (Spleen tyrosine Kinase (SYK))

Alternative Name: SYK

Background: This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Molecular Weight: 72066

Gene ID: 6850

NCBI Accession: NP_001128524, NP_001167638, NP_001167639, NP_003168

UniProt: P43405

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling