RHOC antibody

Catalog No. ABIN6567006

This anti-RHOC antibody is a Rabbit Polyclonal antibody detecting RHOC in WB and IF. Suitable for Human, Mouse and Rat.

Quick Overview for RHOC antibody (ABIN6567006)

Target: RHOC (Ras Homolog Gene Family, Member C (RHOC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHOC antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-RHOC Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human RHOC

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RHOC

Target: RHOC (Ras Homolog Gene Family, Member C (RHOC))

Alternative Name: RHOC

Background:

Synonyms: Aplysia RAS-related homolog 9,ARH 9,ARH9,ARHC,H9,MGC1448,MGC61427,Oncogene RHO H9,Ras homolog gene family member C,RAS related homolog 9,RHO C,Rho cDNA clone 9,Rho related GTP binding protein RhoC,Rho-related GTP-binding protein RhoC,rhoC,RhoC GTPase,RHOC,RHOH 9,RHOH9,Small GTP binding protein RhoC

Background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molecular Weight:

Observed_MW: 22kDa

Calculated_MW: 22kDa

Gene ID: 389

UniProt: P08134

Pathways: WNT Signaling, Cell-Cell Junction Organization