GABRA5 antibody

Catalog No. ABIN6568227

The Rabbit Polyclonal anti-GABRA5 antibody is suitable to detect GABRA5 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for GABRA5 antibody (ABIN6568227)

Target: GABRA5 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 5 (GABRA5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRA5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABRA5 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human GABRA5

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GABRA5

Target: GABRA5 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 5 (GABRA5))

Alternative Name: GABRA5

Background:

Synonyms: GAA 5,GAA5,GABA(A) receptor subunit alpha-5,GABRA 5,Gabra5,Gamma aminobutyric acid GABA A receptor alpha 5,Gamma aminobutyric acid GABA A receptor alpha 5 precursor,Gamma aminobutyric acid receptor alpha 5 subunit precursor GABA A receptor,Gamma-aminobutyric acid receptor subunit alpha-5,GBRA5,GC138184

Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.

Molecular Weight:

Observed_MW: 60kDa

Calculated_MW: 52kDa

Gene ID: 2558

UniProt: P31644

Pathways: Sensory Perception of Sound, Synaptic Membrane