RFC1 antibody

Catalog No. ABIN6568811

Product Details anti-RFC1 Antibody

Target: RFC1 (Replication Factor C (Activator 1) 1, 145kDa (RFC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RFC1 antibody is un-conjugated

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human RFC1 (NP_001191676.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RFC1

Target: RFC1 (Replication Factor C (Activator 1) 1, 145kDa (RFC1))

Alternative Name: RFC1 (RFC1 Products)

Background: This gene encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA-dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Molecular Weight:

Observed_MW: 130kDa

Calculated_MW: 128kDa

Gene ID: 5981

UniProt: P35251

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA, Dicarboxylic Acid Transport