BCL6 antibody (C-Term)

Catalog No. ABIN656985

The Rabbit Polyclonal anti-BCL6 antibody (Clone RB32973) (ABIN656985) specifically detects BCL6 in WB. The antibody is reactive with Human samples.

Quick Overview for BCL6 antibody (C-Term) (ABIN656985)

Target: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL6 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB32973

Product Details anti-BCL6 Antibody

Binding Specificity: AA 676-704, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BCL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 676-704 amino acids from the C-terminal region of human BCL6.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: BCL6 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for BCL6

Target: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Alternative Name: BCL6

Background: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Molecular Weight: 78846

Gene ID: 604

NCBI Accession: NP_001124317, NP_001128210, NP_001697

UniProt: P41182

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus