PPIE antibody

Catalog No. ABIN6570892

The Rabbit Polyclonal anti-PPIE antibody is suitable to detect PPIE in samples from Human, Mouse and Rat. It has been validated for WB and IP.

Quick Overview for PPIE antibody (ABIN6570892)

Target: PPIE (Peptidylprolyl Isomerase E (Cyclophilin E) (PPIE))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIE antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PPIE Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human PPIE

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IP 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPIE

Target: PPIE (Peptidylprolyl Isomerase E (Cyclophilin E) (PPIE))

Alternative Name: PPIE

Background:

Synonyms: Ab1-210,Cyclophilin 33,Cyclophilin E,Cyclophilin-33,CYP 33,CYP33,EC 5.2.1.8,Peptidyl prolyl cis trans isomerase E,Peptidyl-prolyl cis-trans isomerase E,Peptidylprolyl isomerase E (cyclophilin E),Peptidylprolyl isomerase E,PPIase E,PPIE,PPIE,Rotamase E

Background: The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified.

Molecular Weight:

Observed_MW: 33kDa

Calculated_MW: 33kDa/34kDa

Gene ID: 10450

UniProt: Q9UNP9