RASSF5 antibody

Catalog No. ABIN6571110

The Rabbit Polyclonal anti-RASSF5 antibody has been validated for WB and IHC. It is suitable to detect RASSF5 in samples from Human, Mouse and Rat.

Quick Overview for RASSF5 antibody (ABIN6571110)

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASSF5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RASSF5 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human RASSF5

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RASSF5

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Alternative Name: RASSF5

Background:

Synonyms: Maxp 1,MAXP1,MGC10823,MGC17344,New ras effector 1,NORE 1,NORE1A,NORE1B,Novel Ras effector 1,RAP1 Binding Protein,RAPL,Ras association (RalGDS/AF 6) domain family 5,Ras association (RalGDS/AF 6) domain family member 5,Ras association domain containing family protein 5,Ras association domain-containing protein 5,Ras effector like protein,RASF5,RASSF 3,RASSF 5,RASSF3,RASSF5,Regulator for cell adhesion and polarization enriched in lymphoid tissue ,Regulator for cell adhesion and polarization enriched in lymphoid tissues,Tumor suppressor RASSF3

Background: This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 37kDa, 45kDa

Calculated_MW: 30kDa/37kDa/47kDa

Gene ID: 83593

UniProt: Q8WWW0

Pathways: TCR Signaling