MLXIPL antibody

Catalog No. ABIN6571243

The Rabbit Polyclonal anti-MLXIPL antibody (ABIN6571243) specifically detects MLXIPL in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for MLXIPL antibody (ABIN6571243)

Target: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLXIPL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MLXIPL Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human MLXIPL

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MLXIPL

Target: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Alternative Name: MLXIPL

Background:

Synonyms: carbohydrate response element binding protein,bHLHd14,Carbohydrate responsive element binding protein,Class D basic helix-loop-helix protein 14,MIO,MLX interacting protein like,Mlx interactor,MLX-interacting protein-like,MLXIPL,MONDOB,WBS14,WBSCR 14,WBSCR14,Williams Beuren syndrome chromosome region 14,Williams Beuren syndrome chromosome region 14 protein,Williams-Beuren syndrome chromosomal region 14 protein,WS basic helix loop helix leucine zipper protein,WS basic-helix-loop-helix leucine zipper protein,WS bHLH,WS-bHLH

Background: This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 93kDa

Calculated_MW: 62kDa/78kDa/90kDa/92kDa/93kDa

Gene ID: 51085

UniProt: Q9NP71

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process