GFRA4 antibody (AA 156-184)

Catalog No. ABIN657173

There is 1 publication for this product available. The Rabbit Polyclonal anti-GFRA4 antibody is suitable to detect GFRA4 in samples from Human. It has been validated for WB.

Quick Overview for GFRA4 antibody (AA 156-184) (ABIN657173)

Target: GFRA4 (GDNF Family Receptor alpha 4 (GFRA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFRA4 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB33123

Product Details anti-GFRA4 Antibody

Binding Specificity: AA 156-184

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GFRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the Central region of human GFRA4.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-GFRA4 antibody (ABIN657173)

Wang, Guo, Wang, Liu, Zhang, Cui, Wu: "Downregulation of microRNA-483-5p Promotes Cell Proliferation and Invasion by Targeting GFRA4 in Hirschsprung's Disease." in: DNA and cell biology, Vol. 36, Issue 11, pp. 930-937, (2017) (PubMed).

Target Details for GFRA4

Target: GFRA4 (GDNF Family Receptor alpha 4 (GFRA4))

Alternative Name: GFRA4

Background: The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 31670

NCBI Accession: NP_071422, NP_665705

UniProt: Q9GZZ7