GFRA4 antibody (AA 110-190)

Catalog No. ABIN7224216

This Rabbit Polyclonal antibody specifically detects GFRA4 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GFRA4 antibody (AA 110-190) (ABIN7224216)

Target: GFRA4 (GDNF Family Receptor alpha 4 (GFRA4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFRA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GFRA4 Antibody

Binding Specificity: AA 110-190

Purpose: Rabbit Anti-GFRα-4 Polyclonal Antibody

Specificity: GFRα-4 Polyclonal Antibody detects endogenous levels of GFRα-4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human GFRalpha-4 at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GFRA4

Target: GFRA4 (GDNF Family Receptor alpha 4 (GFRA4))

Alternative Name: GFRalpha-4

Background: GFRA4, GDNF family receptor alpha-4, GDNF receptor alpha-4, GDNFR-alpha-4, GFR-alpha-4, Persephin receptorThe protein encoded by GFRA4 (GDNF family receptor alpha 4)is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. GFRA4 is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for GFRA4.

Molecular Weight: 30kD

Gene ID: 64096

UniProt: Q9GZZ7