ENPP2 antibody (AA 401-450)

Catalog No. ABIN6579248

This Rabbit Polyclonal antibody specifically detects ENPP2 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for ENPP2 antibody (AA 401-450) (ABIN6579248)

Target: ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENPP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ENPP2 Antibody

Binding Specificity: AA 401-450

Purpose: Autotaxin Antibody

Specificity: Autotaxin Polyclonal Antibody detects endogenous levels of Autotaxin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human ENPP2. AA range:401-450

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ENPP2

Target: ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))

Alternative Name: ENPP2

Background:

Synonyms: ENPP2; ATX; PDNP2; Ectonucleotide pyrophosphatase/phosphodiesterase family member 2; E-NPP 2; Autotaxin; Extracellular lysophospholipase D; LysoPLD

Background: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008],

Gene Name: ENPP2

Protein Name: Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

Molecular Weight: 98 kDa

Gene ID: 5168

OMIM: 601060

UniProt: Q13822