FGF23 antibody (AA 181-230)

Catalog No. ABIN6579278

The Rabbit Polyclonal anti-FGF23 antibody (ABIN6579278) specifically detects FGF23 in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for FGF23 antibody (AA 181-230) (ABIN6579278)

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF23 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FGF23 Antibody

Binding Specificity: AA 181-230

Purpose: FGF-23 Antibody

Specificity: FGF-23 Polyclonal Antibody detects endogenous levels of FGF-23 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human FGF23. AA range:181-230

Isotype: IgG

Application Details

Application Notes: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FGF23

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Alternative Name: FGF23

Background:

Synonyms: FGF23, HYPF, Fibroblast growth factor 23, FGF-23, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor

Background: gamma-aminobutyric acid type A receptor gamma2 subunit(GABRG2) Homo sapiens This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

Gene Name: FGF23

Protein Name: Fibroblast growth factor 23

Molecular Weight: 27 kDa

OMIM: 605380

UniProt: Q9GZV9

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion