Fascin antibody (AA 261-310)

Catalog No. ABIN6579365

The Rabbit Polyclonal anti-Fascin antibody is suitable to detect Fascin in samples from Human, Rat and Mouse. It has been validated for WB, IHC, IF and ELISA.

Quick Overview for Fascin antibody (AA 261-310) (ABIN6579365)

Target: Fascin (FSCN1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fascin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Product Details anti-Fascin Antibody

Binding Specificity: AA 261-310

Purpose: Fascin 1 Antibody

Specificity: Fascin 1 Polyclonal Antibody detects endogenous levels of Fascin 1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human FSCN1. AA range:261-310

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Fascin

Target: Fascin (FSCN1)

Alternative Name: FSCN1

Background:

Synonyms: FSCN1; FAN1; HSN; SNL; Fascin; 55 kDa actin-bundling protein; Singed-like protein; p55

Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],

Gene Name: FSCN1

Protein Name: Fascin

Molecular Weight: 54 kDa

Gene ID: 6624

UniProt: Q16658