CD1c antibody (AA 211-260)

Catalog No. ABIN6579429

The Rabbit Polyclonal anti-CD1c antibody is suitable to detect CD1c in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for CD1c antibody (AA 211-260) (ABIN6579429)

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1c antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD1c Antibody

Binding Specificity: AA 211-260

Purpose: CD1C Antibody

Specificity: CD1C Polyclonal Antibody detects endogenous levels of CD1C protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD1C. AA range:211-260

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CD1c

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Alternative Name: CD1C

Background:

Synonyms: CD1C, T-cell surface glycoprotein CD1c, CD1c

Background: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands.The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008],

Gene Name: CD1C

Protein Name: T-cell surface glycoprotein CD1c

Molecular Weight: 37 kDa

Gene ID: 911

UniProt: P29017