IL9 Receptor antibody (AA 201-250)

Catalog No. ABIN6579505

The Rabbit Polyclonal anti-IL9 Receptor antibody is suitable to detect IL9 Receptor in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for IL9 Receptor antibody (AA 201-250) (ABIN6579505)

Target: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL9 Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL9 Receptor Antibody

Binding Specificity: AA 201-250

Purpose: IL-9R Antibody

Specificity: IL-9R Polyclonal Antibody detects endogenous levels of IL-9R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human IL9R. AA range:201-250

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for IL9 Receptor

Target: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Alternative Name: IL9R

Background:

Synonyms: IL9R, Interleukin-9 receptor, IL-9 receptor, IL-9R, CD129

Background: The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: IL9R

Protein Name: Interleukin-9 receptor

Molecular Weight: 58 kDa

Gene ID: 3581

OMIM: 603149

UniProt: Q01113

Pathways: JAK-STAT Signaling, Growth Factor Binding