BMPR1A antibody (AA 1-50)

Catalog No. ABIN6579539

This Rabbit Polyclonal antibody specifically detects BMPR1A in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for BMPR1A antibody (AA 1-50) (ABIN6579539)

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMPR1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BMPR1A Antibody

Binding Specificity: AA 1-50

Purpose: CD292 Antibody

Specificity: CD292 Polyclonal Antibody detects endogenous levels of CD292 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human BMPR1A. AA range:1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BMPR1A

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Alternative Name: BMPR1A

Background:

Synonyms: BMPR1A, ACVRLK3, ALK3, Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A, Activin receptor-like kinase 3, ALK-3, Serine/threonine-protein kinase receptor R5, SKR5, CD292

Background: The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008],

Gene Name: BMPR1A

Protein Name: Bone morphogenetic protein receptor type-1A

Molecular Weight: 60 kDa

Gene ID: 657

OMIM: 601299

UniProt: P36894

Pathways: Stem Cell Maintenance