CD207 antibody (AA 61-110)

Catalog No. ABIN6579543

This Rabbit Polyclonal antibody specifically detects CD207 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CD207 antibody (AA 61-110) (ABIN6579543)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD207 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD207 Antibody

Binding Specificity: AA 61-110

Purpose: CD207 Antibody

Specificity: CD207 Polyclonal Antibody detects endogenous levels of CD207 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD207. AA range:61-110

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Alternative Name: CD207

Background:

Synonyms: CD207, CLEC4K, C-type lectin domain family 4 member K, Langerin, CD207

Background: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010],

Gene Name: CD207

Protein Name: C-type lectin domain family 4 member K

Molecular Weight: 36 kDa

Gene ID: 50489

OMIM: 604862

UniProt: Q9UJ71