BCAM antibody (AA 191-240)

Catalog No. ABIN6579555

The Rabbit Polyclonal anti-BCAM antibody (ABIN6579555) specifically detects BCAM in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for BCAM antibody (AA 191-240) (ABIN6579555)

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAM antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BCAM Antibody

Binding Specificity: AA 191-240

Purpose: CD239 Antibody

Specificity: CD239 Polyclonal Antibody detects endogenous levels of CD239 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human BCAM. AA range:191-240

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BCAM

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Alternative Name: BCAM

Background:

Synonyms: BCAM, LU, MSK19, Basal cell adhesion molecule, Auberger B antigen, B-CAM cell surface glycoprotein, F8/G253 antigen, Lutheran antigen, Lutheran blood group glycoprotein, CD239

Background: This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012],

Gene Name: BCAM

Protein Name: Basal cell adhesion molecule

Molecular Weight: 67 kDa

Gene ID: 4059

OMIM: 612773

UniProt: P50895