LAG3 antibody (AA 91-140)

Catalog No. ABIN6579574

The Rabbit Polyclonal anti-LAG3 antibody is suitable to detect LAG3 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for LAG3 antibody (AA 91-140) (ABIN6579574)

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAG3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LAG3 Antibody

Binding Specificity: AA 91-140

Purpose: CD223 Antibody

Specificity: CD223 Polyclonal Antibody detects endogenous levels of CD223 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human LAG3. AA range:91-140

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for LAG3

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Alternative Name: LAG3

Background:

Synonyms: LAG3, FDC, Lymphocyte activation gene 3 protein, LAG-3, Protein FDC, CD223

Background: Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008],

Gene Name: LAG3

Protein Name: Lymphocyte activation gene 3 protein

Molecular Weight: 57 kDa

Gene ID: 3902

OMIM: 153337

UniProt: P18627

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints