PAX5 antibody (AA 171-220)

Catalog No. ABIN6579654

This Rabbit Polyclonal antibody specifically detects PAX5 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for PAX5 antibody (AA 171-220) (ABIN6579654)

Target: PAX5 (Paired Box 5 (PAX5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PAX5 Antibody

Binding Specificity: AA 171-220

Purpose: Pax-5 Antibody

Specificity: Pax-5 Polyclonal Antibody detects endogenous levels of Pax-5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human PAX5. AA range:171-220

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Alternative Name: PAX5

Background:

Synonyms: PAX5, Paired box protein Pax-5, B-cell-specific transcription factor, BSAP

Background: This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation.This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9,14)(p13,q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer

Gene Name: PAX5

Protein Name: Paired box protein Pax-5

Molecular Weight: 42 kDa

Gene ID: 5079

OMIM: 167414

UniProt: Q02548