APEX1 antibody (acLys6)

Catalog No. ABIN6579711

This anti-APEX1 antibody is a Rabbit Polyclonal antibody detecting APEX1 in WB and ELISA. Suitable for Human.

Quick Overview for APEX1 antibody (acLys6) (ABIN6579711)

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APEX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-APEX1 Antibody

Binding Specificity: AA 1-50, acLys6

Specificity:

APE1 (Acetyl-Lys6) Antibody detects endogenous levels of APE1 protein only when acetylated at Lys6.

Acetylation: H:K6

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using acetylated peptide. The antibody against non-acetylated peptide was removed by chromatography using corresponding non-acetylated peptide.

Immunogen: The antiserum was produced against synthesized Acetyl-peptide derived from human APE1 around the Acetylation site of Lys6.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:10000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Target Details for APEX1

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Alternative Name: APE1

Background:

Synonyms: APEX1, APE, APE1, APEX, APX, HAP1, REF1, DNA-(apurinic or apyrimidinic site) lyase, APEX nuclease, APEN, Apurinic-apyrimidinic endonuclease 1, AP endonuclease 1, APE-1, REF-1, Redox factor-1

NCBI Gene Symbol: APEX1

Molecular Weight: 35 kDa

Gene ID: 328

OMIM: 107748

UniProt: P27695

Pathways: DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus