UBP1 antibody (AA 266-295)

Catalog No. ABIN2846933

The Rabbit Polyclonal anti-UBP1 antibody is suitable to detect UBP1 in samples from Human. It has been validated for WB, IHC (p) and IF.

Quick Overview for UBP1 antibody (AA 266-295) (ABIN2846933)

Target: UBP1 (Upstream Binding Protein 1 (LBP-1a) (UBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: RB34155

Product Details anti-UBP1 Antibody

Binding Specificity: AA 266-295

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the Central region of human UBP1.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: UBP1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for UBP1

Target: UBP1 (Upstream Binding Protein 1 (LBP-1a) (UBP1))

Alternative Name: UBP1

Background: UBP1 functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.

Molecular Weight: 60491

Gene ID: 7342

NCBI Accession: NP_001121632, NP_001121633, NP_055332

UniProt: Q9NZI7