Recombinant SPTA1 antibody (AA 356-475)
The Rabbit Monoclonal anti-SPTA1 antibody (Clone SPTA1-2939R) (ABIN6654212) specifically detects SPTA1 in IHC (p), WB and ELISA.
The antibody is reactive with Human samples.
Catalog No. ABIN6654212
$642.40
Plus shipping costs $50.00
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Quick Overview for Recombinant SPTA1 antibody (AA 356-475) (ABIN6654212)
Target
SPTA1
(Spectrin alpha Chain, Erythrocytic 1 (SPTA1))
Antibody Type
Recombinant Antibody
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Conjugate
This SPTA1 antibody is un-conjugated
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), ELISA
Clone
SPTA1-2939R
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Binding Specificity
- AA 356-475
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Purpose
- Recombinant Spectrin alpha 1 Antibody / SPTA1
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Purification
- Protein A affinity chromatography
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Immunogen
- A portion of amino acids 356-475 from the human protein was used as the immunogen for the recombinant Spectrin alpha 1 antibody.
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Isotype
- IgG, kappa
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Application Notes
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Optimal dilution of the recombinant Spectrin alpha 1 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store the recombinant Spectrin alpha 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- SPTA1 (Spectrin alpha Chain, Erythrocytic 1 (SPTA1))
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Alternative Name
- SPTA1 / Spectrin alpha 1
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Background
- Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous and chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin Ia and spectrin Ib are present in erythrocytes, whereas spectrin IIa (also designated fodrin alpha) and spectrin IIb (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.
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UniProt
- P02549
Target
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