Recombinant SPTA1 antibody (AA 356-475)
The Mouse Monoclonal anti-SPTA1 antibody (Clone SCNA-1R) (ABIN6654215) specifically detects SPTA1 in IHC (p) and WB.
The antibody is reactive with Human samples.
Catalog No. ABIN6654215
$642.40
Plus shipping costs $50.00
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Quick Overview for Recombinant SPTA1 antibody (AA 356-475) (ABIN6654215)
Target
SPTA1
(Spectrin alpha Chain, Erythrocytic 1 (SPTA1))
Antibody Type
Recombinant Antibody
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Conjugate
This SPTA1 antibody is un-conjugated
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Clone
SCNA-1R
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Binding Specificity
- AA 356-475
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Purpose
- Recombinant SPTA1 Antibody / Spectrin alpha 1
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Purification
- Protein G affinity chromatography
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Immunogen
- A portion of amino acids 356-475 from the human protein was used as the immunogen for the recombinant SPTA1 antibody.
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Isotype
- IgG1, kappa
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Application Notes
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The stated application concentrations are suggested starting points. Titration of the recombinant SPTA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store the recombinant SPTA1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- SPTA1 (Spectrin alpha Chain, Erythrocytic 1 (SPTA1))
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Alternative Name
- SPTA1 / Spectrin alpha 1
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Background
- This gene encodes a member of a family of molecular scaffold proteins that link the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms a component of the erythrocyte plasma membrane. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3. [RefSeq]
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UniProt
- P02549
Target
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