IL7R antibody (AA 21-236)

Catalog No. ABIN6654530

The Mouse Monoclonal anti-IL7R antibody (Clone IL7R-2751) (ABIN6654530) specifically detects IL7R in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for IL7R antibody (AA 21-236) (ABIN6654530)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL7R antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: IL7R-2751

Product Details anti-IL7R Antibody

Binding Specificity: AA 21-236

Purpose: CD127 Antibody / IL7R

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 21-236 from the human protein was used as the immunogen for the CD127 antibody.

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal dilution of the CD127 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CD127 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Alternative Name: CD127

Background: The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID).

UniProt: P16871

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size