IL7R antibody (AA 21-236)

Catalog No. ABIN6654532

The Mouse Monoclonal anti-IL7R antibody is suitable to detect IL7R in samples from Human. It has been validated for WB and ELISA.

Quick Overview for IL7R antibody (AA 21-236) (ABIN6654532)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL7R antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Clone: IL7R-2751

Product Details anti-IL7R Antibody

Binding Specificity: AA 21-236

Purpose: CD127 Antibody / IL7R (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 21-236 from the human protein was used as the immunogen for the CD127 antibody.

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal dilution of the CD127 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the CD127 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Alternative Name: CD127

Background: The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID).

UniProt: P16871

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size